Alpha JYM

alpha

Testosterone is well known as the most critical anabolic, not to mention androgenic, hormone in the body. It’s what separates the men from the boys. Healthy testosterone levels are critical for guys who want to build muscle mass, boost strength, and drop body fat. Testosterone also keeps a man’s sex drive high and gives him a competitive edge. It’s truly the alpha hormone.

Unfortunately, as we age, our testosterone levels fall sharply. In addition to aging, environmental factors and stress can leave their mark on a man’s testosterone production, causing it to plummet. Men who suffer from a decrease in their body’s testosterone levels may experience lower sex drive, erectile dysfunction, less energy, greater fatigue, decreased focus and concentration, depression, insomnia, a gradual loss of muscle mass and strength, and greater gain of body fat. Evidence also suggests that low testosterone levels may be a major factor in the development of metabolic disease and heart disease.

If you exhibit any of these symptoms, you may be suffering from low testosterone levels. At over 45 years old, my own testosterone has certainly dropped from the levels I had as a younger man. I formulated Alpha JYM for those of us who want a real, fully dosed natural test booster that actually helps increase lagging levels of this powerful alpha hormone.

The Science of Alpha JYM

Like every one of my JYM Supplement Science products, Alpha JYM is a non-proprietary supplement that uses the proper doses of each ingredient and lists it clearly in the supplement facts panel. Each of the six ingredients was chosen based on real scientific data published in peer-reviewed journals and my experience with clients in the gym. Together, these six ingredients work synergistically to increase your body’s natural levels of testosterone through five different processes.

If you’re fairly supplement savvy, then you’ve likely read on message boards and honest product reviews that the majority of testosterone boosters don’t work. You may have even experienced this first-hand. In all honesty, most test boosters don’t work because they don’t contain proper ingredients at right proper doses shown to raise test levels in the lab. Alas, many test boosters tend to be under-dosed, proprietary blends that don’t produce results.

When you read the label of Alpha JYM, you’ll see that it provides a total of 2100 mg (2.1 grams) of active ingredients per dose. When you take it twice per day as directed, it delivers a total of 4,200 mg (4.2 grams!) of active testosterone-raising ingredients. And these ingredients don’t include common vitamins and minerals like vitamin D and zinc, like many “testosterone boosters” provide. Why? Because you should take your vitamins and minerals separately.

When you really want to increase your body’s natural testosterone levels, you want powerful ingredients that boost test safely and effectively. Alpha JYM contains the ingredients and doses I personally use to keep my testosterone levels at a healthy peak for better performance, great results in the gym, and a better quality of life.

Five-Stage Testosterone Boost

Alpha JYM works via five separate mechanisms that act together to significantly raise testosterone levels.

1) First, the ingredients in Alpha JYM encourage your body to produce more testosterone.

2) Next, they blunt estrogen levels, which in turn helps further raise testosterone. They also help prevent the conversion of testosterone into dihydrotestosterone (DHT), which maximizes the anabolic benefits of testosterone.

3) Alpha JYM also protects the testosterone-producing cells in the testicles from oxidative damage. This allows them to function at higher levels to keep testosterone production rate peaked.

4) Alpha JYM’s ingredients also stop the excretion of testosterone from the body. This means you have higher blood testosterone levels for longer.

5) Finally, Alpha JYM liberates extra testosterone from binding proteins that normally keep it from being used by the body, allowing you to put more testosterone to use for greater gains in muscle size and strength.

1. Production
Alpha JYM encourages your body to increase testosterone production in both the brain and in the testicles. In the brain, Alpha JYM enhances the release of luteinizing hormone (LH) from the pituitary gland. LH travels through the bloodstream to the testicles, where it encourages the testicles to ramp up testosterone production. Alpha JYM also works directly on the testicles to increase the activity of key enzymes that convert cholesterol into test. The end result is greater testosterone levels.

2. Inhibition
Alpha JYM also inhibits enzymes that normally convert testosterone into estrogen and DHT. Estrogen is known as the main “female hormone,” but men also have it. Testosterone can be converted into estrogen via the enzyme aromatase. High levels of estrogen can actually decrease testosterone levels. Key ingredients in Alpha JYM inhibit the aromatase enzyme so that less testosterone is converted into estrogen, resulting in higher testosterone levels.

Other ingredients in Alpha JYM inhibit the 5 alpha-reductase enzyme that normally converts testosterone into DHT. While DHT provides some positive male characteristics, such as greater sex drive and higher aggression, it also drives less attractive outcomes like more acne and male-pattern baldness. In addition, higher DHT levels are associated with a greater risk of prostate cancer. DHT stimulates the expression of prostate specific antigen (PSA), which acts as a prostate cancer growth factor.

By converting less testosterone into DHT, you maintain higher anabolic properties from the testosterone you have while negating the downsides of higher DHT levels.

3. Protection
Alpha JYM includes ingredients that prevent oxidative damage to testosterone-producing cells in the testicles. Free radicals can wreak havoc on the cells of the body. This disturbs the cells’ ability to function properly. When the cells of the testicles experience oxidative damage, their testosterone production is significantly reduced. By preventing this oxidative damage, Alpha JYM maintains higher testosterone levels by allowing these specialized cells to function optimally.

4. Freedom
Alpha JYM also boosts test by setting more testosterone free. In the blood, testosterone binds to the carrier protein sex hormone binding globulin (SHBG). This protein allows testosterone to circulate in the blood. However, SHBG holds onto testosterone, often preventing it from leaving the blood and getting to the tissues in the body that need it, such as muscle fibers. In the muscle fibers, testosterone binds to androgen receptors, which instigates processes that lead to muscle growth. By freeing up more testosterone from SHBG, Alpha JYM puts more of your testosterone to work.

5. Sequestering
Alpha JYM also enhances testosterone levels by stopping testosterone excretion. In the body, the enzyme UGT2B17 converts testosterone into a molecule known as testosterone glucuronide. Once testosterone is converted into testosterone glucuronide, it is excreted from the body by the kidneys. In other words, you pee out your testosterone. This lowers your testosterone levels overall. Research shows that quercetin inhibits the ability of UGT2B17 to convert testosterone into testosterone glucuronide, which prevents the loss of testosterone and maintains higher testosterone levels.

Be an Alpha!

I formulated Alpha JYM based on the ingredients and doses I personally use to keep my testosterone levels at the top of the healthy range, even over 45 years old. This formula is what I’ve found to work best through years of experimenting to naturally keep my testosterone levels high while pushing estrogen and DHT levels down. Now you can take advantage of the exact formula that’s worked so well for me and my clients. Use it to wage war in the gym, lead the pack, maximize your results at any age, just like I do.

Hit the JYM!

jim_sig
Jim Stoppani, PhD
Owner
JYM Supplement Science

———————————————————————————————————-

Alpha JYM features:

>> 6 research-backed ingredients provided in their proper doses
>> 1000 milligrams per day of fenugreek to increase your body’s own production of testosterone, increase free testosterone levels, and prevent its conversion to estrogen and DHT
>> 1000 milligrams per day of Ashwagandha root extract to prevent oxidative damage to important testosterone-producing cells for greater testosterone production
>> 1000 milligrams per day of Damiana to blunt the conversion of testosterone to estrogen
>> 500 milligrams of diindolymethane (DIM) to convert strong and damaging forms of estrogen into weaker forms that aren’t harmful to the body
>> 200 milligrams of Eurycoma longifolia extract to further increase both total testosterone and free testosterone levels
>> 500 milligrams of quercetin to prevent testosterone excretion and help you maintain higher testosterone levels for longer
———————————————————————————————————–

Leader of the Pack

Alpha JYM goes head-to-head with the 5 leading testosterone-boosting products on the market today.

Apha JYM
formula
Leading
competitor #1
Leading
competitor #2
Leading
competitor #3
Leading
competitor #4
Leading
competitor #5
1000 mg Fenugreek extract (50% saponins) Fenugreek NOT included Fenugreek NOT included Fenugreek NOT included Fenugreek dose is proprietary Fenugreek dose is proprietary
1000 mg Ashwaganda root (5:1) extract Ashwagandha NOT included Ashwagandha NOT included Ashwagandha NOT included Ashwagandha NOT included Ashwagandha NOT included
1000 mg Damiana Damiana NOT included Damiana NOT included Damiana NOT included Damiana NOT included Damiana NOT included
500 mg Diindolylmethane (DIM) DIM dose is proprietary DIM NOT included DIM dose is proprietary DIM NOT included DIM dose is proprietary
200 mg Eurycoma longifolia (100:1) extract Eurycoma longifolia NOT included Eurycoma longifolia NOT included Eurycoma longifolia NOT included Eurycoma longifolia NOT included Eurycoma longifolia dose is proprietary
500 mg Quercetin Quercetin NOT included Quercetin NOT included Quercetin NOT included Quercetin NOT included Quercetin NOT included

As you can see from this table, the top testosterone-boosting formulas either don’t include most of the critical ingredients to effectively raise test, or have them listed under “proprietary blends,” which means that they’re probably under-dosed. Nothing on the market even comes close to stacking up with the science inside Alpha JYM.

———————————————————————————————————–

Inside Alpha

Let’s get out the microscope and take an even closer look at the six ingredients and doses used to make Apha JYM the most effective natural testosterone booster available.

*1000 mg Fenugreek extract

Numerous studies suggest that men supplementing with fenugreek have an increase in sex drive and sexual satisfaction.

Research also suggests that men supplementing with fenugreek for several weeks experience an increase in testosterone levels.

Fenugreek has a high content of furostanolic saponins, which are phytochemicals that work in the body to increase the release of luteinizing hormone from the pituitary gland, which influences the testicles to increase testosterone production.

Evidence also suggests that fenugreek directly stimulates the testicles to produce more testosterone by increasing the activity of key enzymes involved in converting cholesterol into testosterone.

Fenugreek also frees more testosterone from sex-hormone binding globulin (SHBG) to allow for higher rates of free, bioavailable testosterone.

Studies suggest that fenugreek is effective at reducing the conversion of testosterone to dihydrotestoserone (DHT) and estrogen.

Fenugreek also appears to further enhance testosterone levels through its antioxidant properties. The testicles are quite susceptible to oxidative damage, which can hamper their ability to produce testosterone. Fenugreek helps prevent oxidative damage and keep testosterone production firing at full force.

*200 mg Eurycoma longifolia (100:1) extract

This rainforest plant, also known as Tongkat Ali, has been used to increase male virility and sexual prowess for centuries in Malaysia.

Several studies suggest that supplementing with Eurycoma significantly raises total and free testosterone while simultaneously lowering cortisol. A higher testosterone to cortisol ratio has long been considered a marker of an increased anabolic state.

Research has shown that males with declining testosterone levels given 200 mg of eurycoma extract for one month had an increase in blood testosterone levels of almost 50%.

Eurycoma appears to enhance testosterone levels by a few different mechanisms:

The first is by directly stimulating the testicles to increase testosterone production.

Eurycoma also inhibits the conversion of testosterone into estrogen. One study reported that eurycomanone, the major quassinoid in Eurycoma extract, inhibited the aromatase enzyme to decrease estrogen production and increase testosterone production in the Leydig cells of the testicles.

Eurycoma also frees more testosterone from its carrier protein, sex hormone binding globulin (SHBG). Clinical research suggests that eurycoma significantly lowers SHBG. One study even reported that both men and women over age 55 supplementing with Eurycoma extract for five weeks experienced an increase in free testosterone thanks to the lowering of SHBG. They also made significant gains in strength.

*1000 mg of Ashwagandha root (5:1) extract

Known scientifically as Withania somnifera, the ashwagandha herb has been used in ancient Indian Ayurveda and Unani systems of medicine.

This shrub plant is well known for its adaptogenic effects, which means that it helps the body better deal with stress, such as from exercise, which can help you recover better and grow more.

Newer research shows that ashwagandha also works well to boost test levels. Indian researchers reported that males with normal testosterone levels supplementing with ashwagandha for three months experienced a 15% increase in their testosterone levels at the end of the study. They also found that subjects with low testosterone levels at the start of the study increased their testosterone levels by over 40% after three months.

Other research shows that ashwagandha supplementation leads to an increase in testosterone with a concomitant decrease in cortisol.

The main way ashwagandha raises testosterone levels is by reducing the amount of reactive oxygen species present in testosterone cells. This better preserves the activity of key enzymes involved in testosterone production.

The majority of research on the test-boosting benefits of ashwagandha used a daily dose of 5 grams of root powder. The ashwagandha root extract used in Alpha JYM is a 5:1 concentration. That means the 1000 mg (1 gram) dose provided daily in Alpha JYM is equivalent to the 5 gram dose of root powder used in the studies.

*1000 mg of Damiana

Known scientifically as Turnera diffusa, damiana is a shrub native to Mexico and Central and South America that has been used for centuries as an aphrodisiac.

Damiana works by inhibiting the conversion of testosterone into estrogen.

Research confirms that damiana is a potent aromatase inhibitor, due primarily to the active ingredients pinocembrin and acacetin. This is particularly important as we age since aromatase levels rise with aging.

Research also suggests that damiana exerts a positive effect on nitric oxide (NO) production, which can further benefit sexual performance.

*500 mg of Diindolymethane (DIM)

3,3’-diindolylmethane (DIM) is a naturally occurring plant alkaloid that is formed in the digestive tract from indole glucosinate, which is found in cruciferous vegetables like broccoli, cauliflower, Brussels sprouts, and kale. Digesting these foods leads to the formation of DIM.

Research confirms that DIM provides protection against certain cancers and has a positive influence on estrogen metabolism. DIM works in the body to convert the problematic form of estrogen into a non-problematic form.

In the body, estrogen is broken down into metabolites. The three main metabolites are 2-hydroxyestrone, 4-hydroxyestrone, and 16-hydroxyestrone. These metabolites can have stronger or weaker estrogenic activity. The 2-hydroxyestrone has the weakest estrogenic activity. DIM helps to convert more estrogen into mainly the weaker form of 2-hydroxyestrone.

In other words, DIM helps to convert estrogen into a weaker form that doesn’t have the negative impact associated with estrogen in both males and females.

DIM also works to inhibit DHT from stimulating prostate specific antigen (PSA). This helps to protect from prostate cancer.

*250 mg of Quercetin
Quercetin is a potent antioxidant/flavonoid found naturally in onions, apples, tea, broccoli, citrus fruits, and grapes.

It’s been suggested to help reduce the risk of heart disease and certain cancers, such as prostate cancer, boost immunity, act as an anti-inflammatory, boost blood flow to muscles, and even increase exercise endurance.

It can help increase testosterone levels by inhihibitng the UGT2B17 enzyme, which normally converts testosterone into testosterone glucuronide. Once testosterone glucuronide is formed, it is excreted from the body by the kidneys, which lowers blood testosterone levels. By preventing this converion and excretion of testosterone, quercetin helps to keep testosterone levels higher for longer.

Research also shows that the antioxidant properties of quercetin can help to improve tetosterone production in the testicles.

References
Tsujimura, A. The relationship between testosterone deficiency and men’s health. The World Journal of Men’s Health 31:126–135, 2013.
Shah, J. Erectile dysfunction through the ages. BJU International 90:433–441, 2002.
Cohen, P.G. Aromatase, adiposity, aging and disease. The hypogonadal– metabolic–atherogenic-disease and aging connection. Medical Hypotheses 56, 702–708.2001.
Steels, E., et al. Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation. Phytother Res. 2011
Wilborn, C., et al. Effects of a purported aromatase and 5α-reductase inhibitor on hormone profiles in college-age men. Int J Sport Nutr Exerc Metab. 20(6):457-65, 2010.
Hamden, K., et al. Potential protective effect on key steroidogenesis and metabolic enzymes and sperm abnormalities by fenugreek steroids in testis and epididymis of surviving diabetic rats. Arch Physiol Biochem. 116(3):146-55, 2010.
Bushey, B., et al. Fenugreek Extract Supplementation Has No effect on the Hormonal Profile of Resitance-Trained Males. International Journal of Exercise Science: Conference Proceedings. 2(1):Article 13, 2009.
Arafa, M. H., et al Fenugreek seed powder mitigates cadmium-induced testicular damage and hepatotoxicity in male rats. Exp Toxicol Pathol. 66(7):293-300, 2014.
Ang, H. H., et al. Effects od Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats. Exp Anim 49(1):35-38, 2000.
Ang, H. H., et a. Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice. J Basic Clin Physiol Pharmacol 14(3):301-8, 2003.
Saad J M et al. The effect of Eurycoma longifolia on rat and human testicular steroidogenesis. Dept of Biochem and surgery, Faculty of med, Univ of Malaysia.
Tambi, M. I., et al. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 44 (Suppl 1):226-30, 2012.
George, A. and Henkel, R. Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy. Andrologia. In press, 2014.
Low, B. S., et al. Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. J Ethnopharmacol 149(1):201-7, 2013.
Henkel, R. R., et al. Tongkat Ali as a potential herbal supplement for physically active male and female seniors–a pilot study. Phytother Res 28(4):544-50, 2014.
Talbott, S. M., et al. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. J Int Soc Sports Nutr 10(1):28, 2013.
Ismail, S. B., et al. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evid Based Complement Alternat Med. 2012.
Tambi, M. I. and Imran, M. K. Eurycoma longifolia Jack in managing idiopathic male infertility. Asian J Androl. 12(3):376-80, 2010.
Li, C. H., et al., Evaluation of acute 13- week subchronic toxicity and genotoxicity of the powdered root of Tongkat Ali (Eurycoma longifolia Jack). Evidence-Based Complementary and Alternative Medicine, 2013.
Ahmad, M. K., et al. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Fertil Steril 94(3):989-996, 2010.
Mahdi, A A., et al. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility. Evid Based Complement Alternat Med. 2011.
Gupta, A., et al. Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz. J Ethnopharmacol 149(1):208-14, 2013.
Shukla, K. K., et al. Withania somnifera improves semen quality by combating oxidative stress and cell death and improving essential metal concentrations. Reprod Biomed Online 22(5):421-427, 2011.
Grandhi, A., et al. A comparative pharmacological investigation of ashwagandha and ginseng. J Ethnopharmacol 1994; 44:131–5.
Zhao, J., et al. Anti-aromatase activity of the constituents from damiana (Turnera diffusa). Journal of Ethnopharmacology 120:387–393, 2008.
Zhao, J., et al. Phytochemical investigation of Turnera diffusa. J Nat Prod 70(2):289-92, 2007.
Estrada-Reyes, R., et al. Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males. J Ethnopharmacol 123(3):423-9, 2009.
Arletti, R., et al. Stimulating property of Turnera diffusa and Pfaffia paniculata extracts on the sexual-behavior of male rats. Psychopharmacology (Berl) 143(1):15-9. 1999.
Estrada-Reyes, R., et al. Pro-sexual effects of Turnera diffusa Wild (Turneraceae) in male rats involves the nitric oxide pathway. J Ethnopharmacol 146(1):164-72, 2013.
Bradfield, C. A. and Bjeldames, J. F. Structure-activity relationships of dietary indoles: A proposed mechanismof action as modifiers of xenobiotic metabolism. J Toxicol Environ Health 21:311-322, 1987.
McDannel, R., et al. Chemical and biological properties of indole glucosinolates (glucobrassicin): A review. Food Chem Toxicol 26:59-70, 1988.
Leibelt, D. A., et al. Evaluation of chronic exposure to indole-3-carbinol and absorption-enhanced 3,3’-diindolylmethane in Sprague-Dawley rats. Toxicological Sciences 74, 2003.
Le, H. T., et al. Plant-derived 3,3′-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 278(23):21136-45, 2003.
Davis, J. M., et al. Quercetin reduces susceptibility to influenza infection following stressful exercise. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R505-9.
Matsuno, H., et al. Effect of an oral administration of glucosamine-chondroitin-quercetin. Medical Science Monitor, 2009.
Sharmila, G., et al. Chemopreventive effect of quercetin in MNU and testosterone induced prostate cancer of Sprague-Dawley rats. Nutr Cancer 66(1):38-46, 2014.
Sharmila, G., Chemopreventive effect of quercetin, a natural dietary flavonoid on prostate cancer in in vivo model. Clin Nutr 33(4):718-26, 2014.
Davis J. M., et al. Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7.
Edwards, R. L., et al. Quercetin reduces blood pressure in hypertensive subjects. Journal of Nutrition 137: 2405-2411, 2007.
Jenkinson, C., et al. Red wine and component flavonoids inhibit UGT2B17 in vitro. Nutrition Journal 11:67, 2012.
Bharti, S., et al. Quercetin supplementation restores testicular function and augments germ cell survival in the estrogenized rats. Mol Cell Endocrinol 383(1-2):10-20, 2014.
Aktoz, T., et al. Protective effects of quercetin on testicular torsion/detorsion-induced ischaemia-reperfusion injury in rats. Andrologia 42(6):376-83, 2010.